Dr. Alan Martin

Dr. Babb Dr. Babb Dr. Crandall Dr. Haller Dr. Qi Fu Dr. Levine Dr. Martin Dr. Stone Dr. Zhang

BIOGRAPHICAL SKETCH

Name

Alan William Martin, M.D.

Position

Scientist

INSTITUTION AND LOCATION

DEGREE

YEAR(s)

FIELD OF STUDY

Texas A&M University

BS

1980

Biology

Texas A&M College of Medicine

MD

1984

Medicine

The University of Arkansas for Medical Sciences

Internship

1985

Medicine

UT Southwestern Medical Center, Dallas, Texas

Resident

1988

Adult Neurology

Parkland Hospital

Chief Resident

1988

Neurology

The University of Colorado Health Sciences Center Fellow 1989 Neuromuscular Disease

 

POSITIONS:                          1989-Present               Attending

Baylor University Medical Center Dallas, Texas

                                                1993-Present               Clinical Director

Neuromuscular Center

The Institute for Exercise and Environmental Medicine

Texas Health Presbyterian Hospital

                                                                                    Dallas, Texas

                                                1989-Present               Neurologist and Partner

Texas Neurology, P.A.

                                                                                    Dallas, Texas

CLINICAL RESEARCH:     1996-1999                   Co-Investigator, Multi-Center,

                                                                                    Double-Blinded, Placebo-Controlled

                                                                                    Study of Betaseron in the Treatment                                                                                                                             of Secondary Progressive Multiple

                                                                                    Sclerosis, Berlex Laboratories

                                                1997-1999                   Co-Investigator, A Double-

                                                                                    Blind, Placebo-Controlled, Dose-

                                                                                    Determination, Safety, Tolerability,

                                                                                    and Efficacy Study of Intravenous

                                                                                    Antegren in Patients with Multiple

                                                                                    Sclerosis During an Acute Exacerbation,

                                                                                    Elan Pharmaceuticals

                                                1999                            Co-Investigator, An Open

                                                                                    Label, Safety and Pharmacokinetic

                                                                                    Drug Interaction Study of Intra-

                                                                                    venous Antegren and Intramuscular

                                                                                    Interferon Beta-1A in Subjects with

Multiple Sclerosis, Elan Pharmaceuticals

1999-2000                   Co-Investigator, A  Randomized, Double-Blind, Placebo-Controlled, Safety, Tolerability, and Dose Evaluation Study of Intravenous Antegren (natalizumab) at Two Dose Levels Using Magnetic Resonance Imaging in Subjects with Multiple Sclerosis,Elan Pharmaceuticals

2000-2002                   Co-Investigator, A Multi-Center, Open-Label Antegenicity and Safety Study of a Human Serum Albumin-Free Pre-Formulated Solution of

                                    AVONEX® (Interferon beta-

                                    1a) Administered Intramuscu-

                                    larly to Patients with Relapsing

                                    Multiple Sclerosis, Biogen

2000-2001                   Co-Investigator, A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to

                                                                                    Evaluate the Efficacy, Tolerability,

                                                                                    And Safety of 2 Doses (5mg and

                                                                                    50mg) of Glatiramer Acetate Orally

                                                                                    Administered in Relapsing Remitting

                                                                                    Multiple Sclerosis Patients, Teva

2001-2004                   Co-Investigator, A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Study to

Determine the Safety and Efficacy

Of Natalizumab in Subjects with

Relapsing/Remitting MS, Biogen          

2001-2005                   Co-Investigator, A Randomized,     Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Study to

Determine the Safety and Efficacy

Of Natalizumab, When Added to

Avonex, in Subjects with Relapsing/

Remitting MS, Bioge

2002-2003                   Co-Investigator, A Phase II, Randomized, Double-Blind, Placebo Controlled Study to Evaluate the Preliminary Efficacy, Pharmacokinetics and Immunogenicity of BMS-188667 Administered to Subjects with Relapsing-Remitting MS, Bristol Myers Squibb

2003-2004                   Co-Investigator, A Randomized, Double Blind, Placebo-Controlled, Parallel Group, Safety Study of Natalizumab in Combination with Glatiramer Acetate (GA) in Subjects with Relapsing/Remitting MS, Biogen

2003-2005                   Co-Investigator, A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability and Efficacy of NBI-5788 in Patients with Relapsing Multiple Sclerosis, Neurocrine Biosciences

2003-2004                   Co-Investigator, A Multicenter, Open-Label Immunogenicity and Safety Study of a Serum-Free Pre-Formulated Solution of Avonex® (Interferon beta-1a) Administered Intramuscularly to Patients with Relapsing/Remitting Multiple Sclerosis, Biogen

2004-2005                   Co-Investigator, An Open-Label, Multicenter Extension Study to Evaluate the Safety, Tolerability, and Efficacy of Natalizumab in Subjects with Multiple Sclerosis Who Have Completed Studies C-1801, C-1802, or C-1803, Biogen

2005-2006                   Co-Investigator, A Phase II Randomized, Double-Blinded, Placebo-Controlled, Multi-Center Study of Subcutaneous

                                    Daclizumab in Patients with Active,

                                    Relapsing Forms of Multiple

                                    Sclerosis, PDL Biopharma

2006 to present            Co-Investigator, A Multinational, Multicenter, Randomized, Parallel-Group, Double-Blind, Study to Compare the Efficacy, Tolerability and Safety of Glatiramer Acetate Injection 40 mg/ml to that of Glatiramer Acetate Injection 20 mg/ml Administered Once Daily by Subcutaneous Injection in Subjects with RRMS, Teva Neuroscience

2006                            Co-Investigator An Open-Label, Multicenter, Extension Study to Evaluate the Safety and Tolerability of Natalizumab Following Re-Initiation Of Dosing in Multiple Sclerosis Subjects Who Have Completed Study C-1801, C-1802, or C-1803 and a Dosing Suspension Safety Evaluation.

LICENSURE:                        1985                            The State of Texas

BOARD CERTIFICATION: 1990                           Board Certification, American Board

                                                                                    Of Psychiatry and Neurology

                                                  1994                          Board Certification, American Board                                                                                                                            of Electrodiagnostic Medicine

1996                                                    Board Certification, American Board

Of Psychiatry and Neurology, added

Qualification in Neurophysiology

HONORS:                                                                  Phi Kappa Phi-Honor Society

                                                                                    Outstanding Sophomore, College of                                                                                                                              Medicine

SOCIETIES:                          1986                            American Academy of Neurology                                                                                             1989                            American Medical Association

                                                1989                            Texas Medical Association

                                                1989                            Dallas County Medical Society

1994                            American Association Of Electrodiagnostic Medicine

 

 

PUBLICATIONS:                                                     Martin, A.W. and Ringel, S.P.:

                                                                                    Neuromuscular Junction and Muscle Disease

                                                                                    Prognosis of Neurological Disorders-1992

                                                                                    Eds. Evans, Retal, New York, Oxford

                                                                                    Universal Press, pp. 359-374

 

                                                                                    Martin, A.W., Haller, R.G., Barohn, R.:

                                                                                    Metabolic Myopathies

                                                                                    Current Opinion in Rheumatology

                                                                                    1994, 6:552-558

 rev. 1-2008