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Brody's Syndrome

Periodic Paralysis

Myoadenylate Deaminase Deficiency
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Periodic Paralysis
(HYPOP & HYPP)
source: Ronald G. Haller, MD
There are two forms of periodic paralysis: Hypokalemic and
Hyperkalemic (may be associated with paramyotonia congenita).
Onset of this condition usually occurs from childhood to
adulthood. Clinical features include generalized muscle
weakness with periods of paralysis affecting the arms, legs
and neck (typically early in the morning before breakfast
or during rest following exercise) and may be provoked by
exercise, potassium loading, a cold environment, pregnancy,
glucocorticoids, stress, and ethanol. Symptoms may be relieved
by increasing carbohydrate intake and mild exercise.
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